DP1 Antikörper (N-Term)

Produktnummer ABIN2792602

Dieses Anti-DP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DP1 in WB, IHC und IF. Geeignet für Human, Maus und Rind (Kuh).

Kurzübersicht für DP1 Antikörper (N-Term) (ABIN2792602)

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Reaktivität: Human, Maus, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-DP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: VIGTPQRPAA SNTLVVGSPH TPSTHFASQN QPSDSSPWSA GKRNRKGEKN

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte (Rattus)

Homologie: Cow: 92%, Human: 100%, Mouse: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against TFDP1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TFDP1

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-TFDP1 Antibody Titration: 0.2-1 µg/mL
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 410 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DP1

Target: DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))

Andere Bezeichnung: TFDP1

Hintergrund: The E2F transcription factor family regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors and may have a role in progression of some hepatocellular carcinomas by promoting growth of the tumor cells.
Alias Symbols: DP1, Dp-1, DRTF1
Protein Interaction Partner: UBC, E2F6, E2F4, SIAH1, E2F3, E2F2, E2F1, CDK6, PRPF31, CDK2, CDK1, SOCS3, RB1, PCGF6, RYBP, YAF2, RNF2, ELAVL1, LIN9, LIN54, LIN37, RBL2, SERTAD2, NPDC1, E2F5, TP53, RBL1, CDK3, TP53BP1,
Protein Size: 410

Molekulargewicht: 45 kDa

Gen-ID: 7027

NCBI Accession: NM_007111, NP_009042

UniProt: Q14186

Pathways: Zellzyklus, Mitotic G1-G1/S Phases