Progesterone Receptor Antikörper (N-Term)

Produktnummer ABIN2792555

Dieses Anti-Progesterone Receptor-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Progesterone Receptor in WB. Geeignet für Human.

Kurzübersicht für Progesterone Receptor Antikörper (N-Term) (ABIN2792555)

Target: Progesterone Receptor (PGR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Progesterone Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Progesterone Receptor Antikörper

Bindungsspezifität: N-Term

Sequenz: RAPHVAGGPP SPEVGSPLLC RPAAGPFPGS QTSDTLPEVS AIPISLDGLL

Kreuzreaktivität: Human

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PGR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PGR

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-PGR Antibody Titration: 0.2-1 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 684 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Progesterone Receptor

Target: Progesterone Receptor (PGR)

Andere Bezeichnung: Progesterone receptor

Hintergrund: PGR is a member of the steroid receptor superfamily. The protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.
Alias Symbols: NR3C3, PR
Protein Interaction Partner: BCAS2, SRC, PGR, Dlg4, PARP1, ANP32A, XRCC5, PRKDC, XRCC6, MAGEA11, FKBP5, RBM23, RBM39, KAT2B, BRCA1, STUB1, DNAJC7, PPP5C, FKBP4, BPTF, CDK2, COPS5, NCOA1, UBC, ESR1, NCOA2, CCNA1, NCOA3, STAT3, SP1, Jdp2, Batf3, STAT5B, STAT5A, FGFR2, PRDM2, NCOR2, TAF
Protein Size: 684

Molekulargewicht: 70 kDa

Gen-ID: 5241

NCBI Accession: NM_000926

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration