NFYC Antikörper (C-Term)

Produktnummer ABIN2792552

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch NFYC in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd und Schwein.

Kurzübersicht für NFYC Antikörper (C-Term) (ABIN2792552)

Target: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFYC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NFYC Antikörper

Bindungsspezifität: C-Term

Sequenz: MTSLSPLHPS QQLYQIQQVT MPAGQDLAQP MFIQSANQPS DGQAPQVTGD

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 85%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against NFYC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NFYC

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-NFYC Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 458 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NFYC

Target: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Andere Bezeichnung: NFYC

Hintergrund: NFYC is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. NFYC forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity.
Alias Symbols: HSM, CBFC, HAP5, CBF-C, NF-YC, H1TF2A
Protein Interaction Partner: NFYA, CDK2, UBC, SNX2, NFYB, Cebpb, ELAVL1, GAPDH, KAT2B, TP73, TAF12, TAF11, TAF6, TBPL2, TRIM27, HDAC1, KIAA2018, ARID2, GLTSCR1, GLTSCR1L, ZDHHC17, CIC, POGZ, ATF6, ADNP2, LMO4, SREBF2, SP1, DR1, CSN2, DST, SMAD3, SMAD2, ATF6B, MYC, TBP,
Protein Size: 458

Molekulargewicht: 50 kDa

Gen-ID: 4802

NCBI Accession: NM_001142587

UniProt: Q13952

Pathways: Regulation of Lipid Metabolism by PPARalpha