NFYC Antikörper (C-Term)

Produktnummer ABIN2780913

Produktdetails anti-NFYC Antikörper

Target: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFYC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GTQVVQGQIQ TLATNAQQIT QTEVQQGQQQ FSQFTDGQQL YQIQQVTMPA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against NFYC. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NFYC

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 335 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NFYC

Target: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Andere Bezeichnung: NFYC (NFYC Produkte)

Synonyme: CBF-C antikoerper, CBFC antikoerper, H1TF2A antikoerper, HAP5 antikoerper, HSM antikoerper, NF-YC antikoerper, fb98f01 antikoerper, wu:fb98f01 antikoerper, zgc:55514 antikoerper, cbf-c antikoerper, cbfc antikoerper, h1tf2a antikoerper, hap5 antikoerper, hsm antikoerper, nf-yc antikoerper, NFYC antikoerper, Nfyc antikoerper, nuclear transcription factor Y subunit gamma antikoerper, nuclear transcription factor Y, gamma antikoerper, nuclear transcription factor Y subunit gamma L homeolog antikoerper, nuclear transcription factor-Y gamma antikoerper, nuclear Y/CCAAT-box binding factor C subunit NF-YC antikoerper, NFYC antikoerper, nfyc antikoerper, nfyc.L antikoerper, Nfyc antikoerper

Hintergrund: NFYC is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. NFYC forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity.The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants. Additional regulation, preliminarily supported by the EST database, may be represented by alternative splicing in this subunit.
Alias Symbols: CBF-C, CBFC, DKFZp667G242, FLJ45775, H1TF2A, HAP5, HSM, NF-YC
Protein Interaction Partner: NFYA, CDK2, UBC, SNX2, NFYB, Cebpb, ELAVL1, GAPDH, KAT2B, TP73, TAF12, TAF11, TAF6, TBPL2, TRIM27, HDAC1, KIAA2018, ARID2, GLTSCR1, GLTSCR1L, ZDHHC17, CIC, POGZ, ATF6, ADNP2, LMO4, SREBF2, SP1, DR1, CSN2, DST, SMAD3, SMAD2, ATF6B, MYC, TBP,
Protein Size: 335

Molekulargewicht: 37 kDa

Gen-ID: 4802

NCBI Accession: NM_014223, NP_055038

UniProt: Q13952

Pathways: Regulation of Lipid Metabolism by PPARalpha