STXBP1 Antikörper (Middle Region)

Produktnummer ABIN2792301

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch STXBP1 in WB. Er zeigt eine Reaktivität gegenüber Human, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen und Pferd.

Kurzübersicht für STXBP1 Antikörper (Middle Region) (ABIN2792301)

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Reaktivität: Human, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STXBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-STXBP1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: TRSSASFSTT AVSARYGHWH KNKAPGEYRS GPRLIIFILG GVSLNEMRCA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against STXBP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human STXBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 594 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu STXBP1

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Andere Bezeichnung: STXBP1

Hintergrund: STXBP1 belongs to the STXBP/unc-18/SEC1 family. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. The protein is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4.
Alias Symbols: MUNC18-1, UNC18, hUNC18, rbSec1, P67, NSEC1, RBSEC1
Protein Interaction Partner: STX19, SYTL4, TRIM38, STX11, STX1A, APBA2, APBA1, UBC, SQSTM1, DYT10, IQCB1, Htt, KCTD3, APP, STX3, STX2, USO1, DOC2B, DOC2A, CDK5R1, PLD2, PLD1, STX1B, PRKCG, PRKCB, PRKCA, NEFM, NEFH, MAPT, CDK5, HGS, Stx5, Dlg4, STX4, TUBB2A, TUBA4A,
Protein Size: 594

Molekulargewicht: 67 kDa

Gen-ID: 6812

NCBI Accession: NM_001032221, NP_001027392

UniProt: P61764

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport