Serotonin Receptor 3A Antikörper (N-Term)

Produktnummer ABIN2792275

Der Kaninchen Polyklonal Anti-Serotonin Receptor 3A-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Serotonin Receptor 3A in Proben von Human, Ratte, Maus, Hund, Rind (Kuh) und Pferd zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Serotonin Receptor 3A Antikörper (N-Term) (ABIN2792275)

Target: Serotonin Receptor 3A (HTR3A)

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Serotonin Receptor 3A Antikörper

Bindungsspezifität: N-Term

Sequenz: LLLPTLLAQG EARRSRNTTR PALLRLSDYL LTNYRKGVRP VRDWRKPTTV

Homologie: Cow: 78%, Dog: 78%, Horse: 91%, Human: 100%, Mouse: 78%, Rat: 78%

Produktmerkmale: This is a rabbit polyclonal antibody against HTR3A. It was validated on Western Blot using a cell lysate as a positive control.

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR3A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 478 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Serotonin Receptor 3A Antikörper (ABIN2792275)

Rinaldi, Chiaravalli, Mian, Zucca, Tibiletti, Capella, Bertoni: "Serotonin receptor 3A expression in normal and neoplastic B cells." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 77, Issue 3, pp. 129-35, (2010) (PubMed).

Details zu Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Andere Bezeichnung: HTR3A

Hintergrund: HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R
Protein Interaction Partner: HSPA5, CANX,
Protein Size: 478

Molekulargewicht: 55 kDa

Gen-ID: 3359

NCBI Accession: NM_000869, NP_000860

UniProt: P46098

Pathways: Synaptic Membrane