CHRNA9 Antikörper (N-Term)

Produktnummer ABIN2792251

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CHRNA9 in WB. Es zeigt Reaktivität gegenüber Proben von Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio).Es wurde in 1 Publikation zitiert.

Kurzübersicht für CHRNA9 Antikörper (N-Term) (ABIN2792251)

Target: CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))

Reaktivität: Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CHRNA9 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CHRNA9 Antibody - N-terminal region

Sequenz: MNWSHSCISF CWIYFAASRL RAAETADGKY AQKLFNDLFE DYSNALRPVE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Mouse: 93%, Rabbit: 100%, Zebrafish: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against CHRNA9. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA9

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CHRNA9 Antikörper (ABIN2792251)

Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

Details zu CHRNA9

Target: CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))

Andere Bezeichnung: CHRNA9

Hintergrund:

Targeted Subunit: alpha-9

Background Information: CHRNA9 is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor superfamily. CHRNA9 is a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. It is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea.This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells.

Gene Name: Cholinergic receptor, nicotinic, alpha 9 (neuronal)

Alternative Symbols: NACHRA9, HSA243342

Protein Name: Neuronal acetylcholine receptor subunit alpha-9

Molekulargewicht: 55 kDa

Gen-ID: 55584

NCBI Accession: NP_060051

UniProt: Q9UGM1

Pathways: Sensory Perception of Sound