CHRNA9 Antikörper (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal)) (AA 8-42)

Details for Product anti-CHRNA9 Antibody No. ABIN1944733, Anbieter: Anmelden zum Anzeigen
Antigen
  • HSA243342
  • NACHRA9
  • 2410015I05Rik
  • Acra9
  • EG666827
  • Gm8311
  • cholinergic receptor nicotinic alpha 9 subunit
  • cholinergic receptor, nicotinic, alpha polypeptide 9
  • CHRNA9
  • Chrna9
Epitop
AA 8-42, N-Term
12
4
2
1
1
1
1
Reaktivität
Human
25
10
6
5
3
3
3
3
2
2
2
1
1
Wirt
Kaninchen
25
1
Klonalität (Klon)
Polyklonal ()
Applikation
Western Blotting (WB)
24
9
6
5
3
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This CHRNA9 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 8-42 AA from the N-terminal region of human CHRNA9.
Klon RB46802
Isotyp Ig
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Plasmids, Primers & others Plasmide, Primers & weitere CHRNA9 products on genomics-online (e.g. as negative or positive controls)
Andere Bezeichnung CHRNA9 (CHRNA9 Antibody Abstract)
Hintergrund Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion.
Synonyms: Neuronal acetylcholine receptor subunit alpha-9, Nicotinic acetylcholine receptor subunit alpha-9, NACHR alpha-9, CHRNA9, NACHRA9
Molekulargewicht 54807 Da
Gen-ID 55584
UniProt Q9UGM1
Pathways Sensory Perception of Sound
Applikations-hinweise WB - 1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Bilder des Herstellers
Western Blotting (WB) image for anti-Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9) (AA 8-42), (N-Term) antibody (ABIN1944733) anti-Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9) (AA 8-42), (N-Term) antibody
Produkt verwendet in: Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, 2005 (PubMed).

Peng, Ferris, Matthews, Hiel, Lopez-Albaitero, Lustig: "Characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) and alpha (alpha) 10 (CHRNA10) in lymphocytes." in: Life sciences, Vol. 76, Issue 3, pp. 263-80, 2004 (PubMed).

Lustig, Peng: "Chromosome location and characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) gene." in: Cytogenetic and genome research, Vol. 98, Issue 2-3, pp. 154-9, 2003 (PubMed).

Sgard, Charpantier, Bertrand, Walker, Caput, Graham, Bertrand, Besnard: "A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit." in: Molecular pharmacology, Vol. 61, Issue 1, pp. 150-9, 2001 (PubMed).

Nguyen, Ndoye, Grando: "Novel human alpha9 acetylcholine receptor regulating keratinocyte adhesion is targeted by Pemphigus vulgaris autoimmunity." in: The American journal of pathology, Vol. 157, Issue 4, pp. 1377-91, 2000 (PubMed).

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