Serotonin Receptor 4 Antikörper (Middle Region)

Produktnummer ABIN2792249

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Serotonin Receptor 4 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Rind (Kuh), Schwein, Hund, Pferd und Kaninchen.

Kurzübersicht für Serotonin Receptor 4 Antikörper (Middle Region) (ABIN2792249)

Target: Serotonin Receptor 4 (HTR4)

Reaktivität: Human, Ratte, Rind (Kuh), Schwein, Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Serotonin Receptor 4 Antikörper

Bindungsspezifität: Middle Region

Sequenz: GCWVIPTFIS FLPIMQGWNN IGIIDLIEKR KFNQNSNSTY CVFMVNKPYA

Homologie: Cow: 88%, Dog: 100%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against HTR4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HTR4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 388 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Serotonin Receptor 4

Target: Serotonin Receptor 4 (HTR4)

Andere Bezeichnung: HTR4

Hintergrund: HTR4 is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The protein is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined.This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined.
Alias Symbols: 5-HT4, 5-HT4R
Protein Interaction Partner: UBC, HTR4, ADRB2,
Protein Size: 388

Molekulargewicht: 44 kDa

Gen-ID: 3360

NCBI Accession: NM_000870, NP_000861

UniProt: Q13639

Pathways: JAK-STAT Signalweg, cAMP Metabolic Process, S100 Proteine