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CHM Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-CHM-Antikörper wurde für WB validiert. Er ist geeignet, CHM in Proben von Human und Pferd zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN2792245

Kurzübersicht für CHM Antikörper (N-Term) (ABIN2792245)

Target

Alle CHM Antikörper anzeigen
CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Reaktivität

  • 30
  • 6
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
Human, Pferd

Wirt

  • 27
  • 3
Kaninchen

Klonalität

  • 28
  • 2
Polyklonal

Konjugat

  • 15
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CHM Antikörper ist unkonjugiert

Applikation

  • 17
  • 13
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    LHVDSRSYYG GNWASFSFSG LLSWLKEYQE NSDIVSDSPV WQDQILENEE

    Homologie

    Horse: 80%, Human: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against CHM. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human CHM
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 653 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ishiguro, Yamamoto, Fujita, Akasu, Kobayashi, Moriya: "Effect of a clinical pathway after laparoscopic surgery for colorectal cancer." in: Hepato-gastroenterology, Vol. 55, Issue 85, pp. 1315-9, (2008) (PubMed).

  • Target

    CHM (Choroideremia (Rab Escort Protein 1) (CHM))

    Andere Bezeichnung

    CHM

    Hintergrund

    CHM binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.The choroideremia gene encodes for a protein, the Rab escort protein-1 (REP1), which is involved in membrane trafficking.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: DXS540, FLJ38564, GGTA, HSD-32, MGC102710, REP-1, TCD
    Protein Interaction Partner: UBC, RAB1B, RAB32, RAB14, RAB3D, RAB7A, RAB18, RAB5B, RAB6A, RAB4A, RAB3B, RAB3A, RAB5A, RAB1A,
    Protein Size: 653

    Molekulargewicht

    73 kDa

    Gen-ID

    1121

    NCBI Accession

    NM_000390, NP_000381

    UniProt

    P24386

    Pathways

    Sensory Perception of Sound
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