TRAF4 Antikörper (Middle Region)

Produktnummer ABIN2792211

Produktdetails anti-TRAF4 Antikörper

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LEAPGGWLDH SNTSLGINTP VNGSPVCLEA WDPASAGPAR FSLSLLLFFL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TRAF4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRAF4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 470 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRAF4

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Andere Bezeichnung: TRAF4 (TRAF4 Produkte)

Hintergrund: TRAF4 is a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. It has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CART1, MLN62, RNF83
Protein Interaction Partner: HOMEZ, BYSL, REXO1L6P, PKD1P1, KANSL1, BCL6B, UBL4B, KRT40, FBXL18, BANP, SPDL1, ALKBH4, WBP11, ZNF581, ISYNA1, TBC1D7, GORASP2, EXOC7, BAHD1, WWP2, WWP1, MRPL28, NOS1AP, TRAF4, UBL4A, ZNF3, SUMO1, UBC, TYK2, TP53BP2, QARS, KRT31, ARNT2, TRAF2, USP15, TGF
Protein Size: 470

Molekulargewicht: 53 kDa

Gen-ID: 9618

NCBI Accession: NM_004295, NP_004286

UniProt: Q9BUZ4