CXCL14 Antikörper (Middle Region)

Produktnummer ABIN2792192

Produktdetails anti-CXCL14 Antikörper

Target: CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

Bindungsspezifität: Middle Region

Reaktivität: Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCL14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PHCEEKMVII TTKSVSRYRG QEHCLHPKLQ STKRFIKWYN AWNEKRRVYE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CXCL14. It was validated on Western Blot.

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CXCL14

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 111 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CXCL14 Antikörper (ABIN2792192)

Lietz, Bayer, Ontikatze, Johrden, Tenbusch, Storcksdieck Genannt Bonsmann, Uberla, Dittmer, Wildner: "Codelivery of the chemokine CCL3 by an adenovirus-based vaccine improves protection from retrovirus infection." in: Journal of virology, Vol. 86, Issue 3, pp. 1706-16, (2012) (PubMed).

Perrone, Mattocks, Plummer, Chittur, Mohney, Vignola, Orentreich, Orentreich: "Genomic and metabolic responses to methionine-restricted and methionine-restricted, cysteine-supplemented diets in Fischer 344 rat inguinal adipose tissue, liver and quadriceps muscle." in: Journal of nutrigenetics and nutrigenomics, Vol. 5, Issue 3, pp. 132-57, (2012) (PubMed).

Takahashi, Takahashi, Takahashi, Zolotaryov, Hong, Iida, Okimura, Kaji, Chihara: "CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity." in: Biochemical and biophysical research communications, Vol. 364, Issue 4, pp. 1037-42, (2007) (PubMed).

Details zu CXCL14

Target: CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

Andere Bezeichnung: CXCL14 (CXCL14 Produkte)

Hintergrund: CXCL14 belongs to the cytokine family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation.
Alias Symbols: BMAC, BRAK, KEC, KS1, MGC10687, MIP-2g, MIP2G, NJAC, SCYB14
Protein Interaction Partner: TEX11, TRIM23, REL, APP,
Protein Size: 111

Molekulargewicht: 9 kDa

Gen-ID: 9547

NCBI Accession: NM_004887, NP_004878

UniProt: O95715

Pathways: Autophagie