c-FOS Antikörper (N-Term)

Produktnummer ABIN2792182

Produktdetails anti-c-FOS Antikörper

Target: c-FOS (c-Fos) (c-Fos)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser c-FOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MFSGFNADYE ASSSRCSSAS PAGDSLSYYH SPADSFSSMG SPVNAQDFCT

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FOS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FOS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 380 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu c-FOS

Target: c-FOS (c-Fos) (c-Fos)

Andere Bezeichnung: FOS (c-Fos Produkte)

Synonyme: AP-1 antikoerper, C-FOS antikoerper, p55 antikoerper, c-fos antikoerper, D12Rfj1 antikoerper, cFos antikoerper, cFOS antikoerper, fos antikoerper, Fos proto-oncogene, AP-1 transcription factor subunit antikoerper, FBJ osteosarcoma oncogene antikoerper, proto-oncogene c-Fos-like antikoerper, FOS antikoerper, Fos antikoerper, LOC101078177 antikoerper

Hintergrund: The Fos family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The family members are leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: c-fos, p55, AP-1, C-FOS
Protein Interaction Partner: Psma4, CENPO, LMO3, ARFGAP1, USF2, USF1, PSMC5, PRKAA2, JUNB, JUN, GNG11, NQO1, ATF2, AQP1, LUZP4, CYTH4, CREB5, ABL1, CLU, ATP5I, APP, MTERF4, ANP32E, ARL6IP4, COPS4, CABP1, ZNF133, SET, NEFM, MAP1B, JUND, HSPA1A, MAF, FOS, DDIT3, CEBPG, CEBPE, CEBPA, AT
Protein Size: 380

Molekulargewicht: 41 kDa

Gen-ID: 2353

NCBI Accession: NM_005252, NP_005243

UniProt: P01100

Pathways: S100 Proteine