14-3-3 theta Antikörper (N-Term)

Produktnummer ABIN2792144

Der Kaninchen Polyklonal anti-14-3-3 theta Antikörper wird verwendet zum Nachweis von 14-3-3 theta in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio) und Meerschweinchen. Er wurde validiert für WB und IHC.

Kurzübersicht für 14-3-3 theta Antikörper (N-Term) (ABIN2792144)

Target: 14-3-3 theta (YWHAQ)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser 14-3-3 theta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-14-3-3 theta Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: YWHAQ Antibody - N-terminal region

Sequenz: SVAYKNVVGG RRSAWRVISS IEQKTDTSDK KLQLIKDYRE KVESELRSIC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against YWHAQ. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAQ

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu 14-3-3 theta

Target: 14-3-3 theta (YWHAQ)

Andere Bezeichnung: YWHAQ

Hintergrund:

Background Information: YWHAQ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

Gene Name: Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

Alternative Symbols: 1C5, HS1, 14-3-3

Protein Name: 14-3-3 protein theta

Molekulargewicht: 28kDa

Gen-ID: 10971

NCBI Accession: NP_006817

UniProt: P27348

Pathways: Apoptose, Myometrial Relaxation and Contraction