RIPK2 Antikörper (Middle Region)
-
- Target Alle RIPK2 Antikörper anzeigen
- RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
-
Bindungsspezifität
- Middle Region
-
Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser RIPK2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Sequenz
- LRQERKRPLL DLHIELNGYM YDWNSRVSAK EKYYVWLQHT LRKKLILSYT
- Homologie
- Cow: 85%, Dog: 85%, Guinea Pig: 78%, Horse: 85%, Human: 85%, Mouse: 78%, Rabbit: 84%, Rat: 78%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RIPK2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human RIPK2
- Top Product
- Discover our top product RIPK2 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 540 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
- Andere Bezeichnung
- RIPK2 (RIPK2 Produkte)
- Synonyme
- RIPK2 antikoerper, 2210420D18Rik antikoerper, CARD3 antikoerper, CARDIAK antikoerper, CCK antikoerper, D4Bwg0615e antikoerper, RICK antikoerper, RIP2 antikoerper, GIG30 antikoerper, receptor interacting serine/threonine kinase 2 antikoerper, receptor (TNFRSF)-interacting serine-threonine kinase 2 antikoerper, receptor-interacting serine-threonine kinase 2 antikoerper, RIPK2 antikoerper, Ripk2 antikoerper
- Hintergrund
-
RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
Protein Interaction Partner: RIPK2, XIAP, UBC, TRAF3, KDM3A, PRMT2, PELI3, NOD1, MAP3K7, CHUK, LRRK2, NOD2, TRAF4, TRAF6, MAP3K4, CASP12, NAT16, RNF31, RIPK1, MAVS, TRAF2, TAB2, TAB1, IKBKG, BIRC3, BIRC2, CARD16, CARD6, UBE2I, SMURF1, CFLAR, BCL10, TLR4, TLR2, TRAF5, CASP8, TRAF1, SM
Protein Size: 540 - Molekulargewicht
- 61 kDa
- Gen-ID
- 8767
- NCBI Accession
- NM_003821, NP_003812
- UniProt
- O43353
- Pathways
- T-Zell Rezeptor Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades
-