RIPK2 Antikörper (Middle Region)

Produktnummer ABIN2792136

Der Kaninchen Polyklonal Anti-RIPK2-Antikörper wurde für WB und IF validiert. Er ist geeignet, RIPK2 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen und Meerschweinchen zu detektieren.

Kurzübersicht für RIPK2 Antikörper (Middle Region) (ABIN2792136)

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIPK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-RIPK2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: LRQERKRPLL DLHIELNGYM YDWNSRVSAK EKYYVWLQHT LRKKLILSYT

Homologie: Cow: 85%, Dog: 85%, Guinea Pig: 78%, Horse: 85%, Human: 85%, Mouse: 78%, Rabbit: 84%, Rat: 78%

Produktmerkmale: This is a rabbit polyclonal antibody against RIPK2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RIPK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 540 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RIPK2

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Andere Bezeichnung: RIPK2

Hintergrund: RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
Protein Interaction Partner: RIPK2, XIAP, UBC, TRAF3, KDM3A, PRMT2, PELI3, NOD1, MAP3K7, CHUK, LRRK2, NOD2, TRAF4, TRAF6, MAP3K4, CASP12, NAT16, RNF31, RIPK1, MAVS, TRAF2, TAB2, TAB1, IKBKG, BIRC3, BIRC2, CARD16, CARD6, UBE2I, SMURF1, CFLAR, BCL10, TLR4, TLR2, TRAF5, CASP8, TRAF1, SM
Protein Size: 540

Molekulargewicht: 61 kDa

Gen-ID: 8767

NCBI Accession: NM_003821, NP_003812

UniProt: O43353

Pathways: T-Zell Rezeptor Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades