PDZD3 Antikörper (C-Term)

Produktnummer ABIN2791850

Der Kaninchen Polyklonal anti-PDZD3 Antikörper wird verwendet zum Nachweis von PDZD3 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für PDZD3 Antikörper (C-Term) (ABIN2791850)

Target: PDZD3 (PDZ Domain Containing 3 (PDZD3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDZD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDZD3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PDZD3 Antibody - C-terminal region

Sequenz: APLAEGWALP TKPRCLHLEK GPQGFGFLLR EEKGLDGRPG QFLWEVDPGL

Homologie: Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PDZD3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDZD3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP71359-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PDZD3

Target: PDZD3 (PDZ Domain Containing 3 (PDZD3))

Andere Bezeichnung: PDZD3

Hintergrund:

Background Information: Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR, MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation.

Alternative Symbols: IKEPP, PDZK2, NHERF4

Molekulargewicht: 62kDa

Gen-ID: 79849

UniProt: Q86UT5