PDZD3 Antikörper (AA 258-285)

Produktnummer ABIN1538201

Der Kaninchen Polyklonal anti-PDZD3 Antikörper wird verwendet zum Nachweis von PDZD3 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für PDZD3 Antikörper (AA 258-285) (ABIN1538201)

Target: PDZD3 (PDZ Domain Containing 3 (PDZD3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDZD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB37960

Produktdetails anti-PDZD3 Antikörper

Bindungsspezifität: AA 258-285

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PDZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-285 amino acids from the Central region of human PDZD3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PDZD3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu PDZD3

Target: PDZD3 (PDZ Domain Containing 3 (PDZD3))

Andere Bezeichnung: PDZD3

Hintergrund: Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR, MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).

Gen-ID: 79849

NCBI Accession: NP_001161940, NP_079067

UniProt: Q86UT5