PDZD3 Antikörper (C-Term)

Produktnummer ABIN2791850

Produktdetails anti-PDZD3 Antikörper

Target: PDZD3 (PDZ Domain Containing 3 (PDZD3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDZD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: APLAEGWALP TKPRCLHLEK GPQGFGFLLR EEKGLDGRPG QFLWEVDPGL

Homologie: Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PDZD3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDZD3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDZD3

Target: PDZD3 (PDZ Domain Containing 3 (PDZD3))

Andere Bezeichnung: PDZD3 (PDZD3 Produkte)

Hintergrund: Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR, MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation.
Protein Interaction Partner: SPRYD7, ASAP3, SLC41A3, CACNA1S, PTGIR, SLC22A4, SLCO1A2, SLC15A2, SLCO1C1, GUCY2C, SLCO3A1, SLC22A9, SLC22A3, SLC22A5, CFTR, ABCC2, SLC15A1,
Protein Size: 571

Molekulargewicht: 62 kDa

Gen-ID: 79849

UniProt: Q86UT5