HIST1H2AE Antikörper (N-Term)

Produktnummer ABIN2791579

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HIST1H2AE in WB. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh), Ratte, Maus, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Pferd und Hund.

Kurzübersicht für HIST1H2AE Antikörper (N-Term) (ABIN2791579)

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Reaktivität: Human, Rind (Kuh), Ratte, Maus, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIST1H2AE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HIST1H2AE Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: HIST1H2AE Antibody - N-terminal region

Sequenz: GKQGGKARAK AKTRSSRAGL QFPVGRVHRL LRKGNYSERV GAGAPVYLAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HIST1H2AE. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HIST1H2AE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP70539-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu HIST1H2AE

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Andere Bezeichnung: HIST1H2AE

Hintergrund:

Background Information: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Alternative Symbols: H2A.1, H2A.2, H2A/a, H2AC4, H2AFA, HIST1H2AE

Protein Name: Histone H2A type 1-B/E

Molekulargewicht: 14kDa

Gen-ID: 3012

NCBI Accession: NP_066390

UniProt: P04908

Pathways: Telomere Maintenance