HIST1H2AE Antikörper (Middle Region)

Produktnummer ABIN2788645

Der Kaninchen Polyklonal anti-HIST1H2AE Antikörper (ABIN2788645) detektiert spezifisch HIST1H2AE in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Rind (Kuh), Ratte und Schwein.

Kurzübersicht für HIST1H2AE Antikörper (Middle Region) (ABIN2788645)

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Reaktivität: Human, Rind (Kuh), Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIST1H2AE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HIST1H2AE Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: HIST1H2AE Antibody - middle region

Sequenz: TAEILELAGN AARDNKKTRI IPRHLQLAIR NDEELNKLLG RVTIAQGGVL

Homologie: Cow: 100%, Human: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HIST1H2AE. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60986-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu HIST1H2AE

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Andere Bezeichnung: HIST1H2AE

Hintergrund:

Background Information: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Gene Name: Histone cluster 1, H2ae

Alternative Symbols: H2A.1, H2A.2, H2A/a, H2AC4, H2AFA, HIST1H2AE

Protein Name: Histone H2A type 3

Molekulargewicht: 14kDa

Gen-ID: 3012

NCBI Accession: NP_066390

UniProt: Q7L7L0

Pathways: Telomere Maintenance