C1orf86 Antikörper (C-Term)

Produktnummer ABIN2791345

Produktdetails anti-C1orf86 Antikörper

Target: C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1orf86 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ARSLPQRPAP DPCRAPRVEQ QPSVEGAAAL RSCPMCQKEF APRLTQLDVD

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against C1orf86. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human C1orf86

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 180 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu C1orf86

Target: C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))

Andere Bezeichnung: C1orf86 (C1ORF86 Produkte)

Synonyme: FAAP20 antikoerper, FP7162 antikoerper, Fanconi anemia core complex associated protein 20 antikoerper, FAAP20 antikoerper

Hintergrund: C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
Alias Symbols: FP7162
Protein Interaction Partner: FANCL, FANCA, UBC, FANCC, APITD1, C19orf40, C17orf70, FANCM, REV1, FANCG, FANCF, FANCB, FANCE, ELAVL1,
Protein Size: 180

Molekulargewicht: 19 kDa

Gen-ID: 199990

NCBI Accession: NM_182533, NP_872339

UniProt: Q6NZ36