KNSTRN Antikörper (N-Term)

Produktnummer ABIN2791245

Dieses Anti-KNSTRN-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KNSTRN in WB. Geeignet für Human.

Kurzübersicht für KNSTRN Antikörper (N-Term) (ABIN2791245)

Target: KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KNSTRN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KNSTRN Antikörper

Bindungsspezifität: N-Term

Sequenz: YRKFLFETQA ADLAGGTTVA AGNLLNESEK DCGQDRRAPG VQPCRLVTMT

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against C15orf23. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human C15orf23

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 316 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KNSTRN

Target: KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))

Andere Bezeichnung: C15orf23

Hintergrund: C15orf23 is an essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. It promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
Alias Symbols: SKAP, TRAF4AF1, C15orf23
Protein Interaction Partner: UBC, CLU, CHMP1B, MAPK6, Cep152, Cep55, Dynll1, Mad2l1, Spag5, Knstrn, Plk1, MPHOSPH6, MPP6,
Protein Size: 316

Molekulargewicht: 35 kDa

Gen-ID: 90417

NCBI Accession: NM_033286, NP_150628

UniProt: Q9Y448

Pathways: M Phase