KNSTRN Antikörper (Middle Region)
Kurzübersicht für KNSTRN Antikörper (Middle Region) (ABIN2791244)
Target
Alle KNSTRN Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- TDTATRRNVR KGYKPLSKQK SEEELKDKNQ LLEAVNKQLH QKLTETQGEL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 79%, Yeast: 82%
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Produktmerkmale
- This is a rabbit polyclonal antibody against C15orf23. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human C15orf23
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 316 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
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Andere Bezeichnung
- C15orf23
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Hintergrund
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C15orf23 is an essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. It promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
Alias Symbols: SKAP, TRAF4AF1, C15orf23
Protein Interaction Partner: UBC, CLU, CHMP1B, MAPK6, Cep152, Cep55, Dynll1, Mad2l1, Spag5, Knstrn, Plk1, MPHOSPH6, MPP6,
Protein Size: 316 -
Molekulargewicht
- 35 kDa
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Gen-ID
- 90417
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NCBI Accession
- NM_033286, NP_150628
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UniProt
- Q9Y448
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Pathways
- M Phase
Target
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