Deltex Homolog 4 Antikörper (C-Term)
Kurzübersicht für Deltex Homolog 4 Antikörper (C-Term) (ABIN2791002)
Target
Alle Deltex Homolog 4 (DTX4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- LPVCLTRPPK LVLHPPPVSK SEIKSIPGVS NTSRKTTKKQ AKKGKTPEEV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against DTX4. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human DTX4
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 619 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))
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Andere Bezeichnung
- DTX4
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Hintergrund
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DTX4 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
Alias Symbols: RNF155
Protein Interaction Partner: HSP90AA1, NLRP4, TBK1,
Protein Size: 619 -
Molekulargewicht
- 67 kDa
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Gen-ID
- 23220
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NCBI Accession
- NM_015177, NP_055992
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UniProt
- Q9Y2E6
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Pathways
- Notch Signalweg
Target
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