Deltex Homolog 4 Antikörper (C-Term)
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- Target Alle Deltex Homolog 4 (DTX4) Antikörper anzeigen
- Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Ratte, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Deltex Homolog 4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LPVCLTRPPK LVLHPPPVSK SEIKSIPGVS NTSRKTTKKQ AKKGKTPEEV
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against DTX4. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human DTX4
- Top Product
- Discover our top product DTX4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 619 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))
- Andere Bezeichnung
- DTX4 (DTX4 Produkte)
- Hintergrund
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DTX4 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
Alias Symbols: RNF155
Protein Interaction Partner: HSP90AA1, NLRP4, TBK1,
Protein Size: 619 - Molekulargewicht
- 67 kDa
- Gen-ID
- 23220
- NCBI Accession
- NM_015177, NP_055992
- UniProt
- Q9Y2E6
- Pathways
- Notch Signalweg
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