YTHDF2 Antikörper (C-Term)

Produktnummer ABIN2790892

Produktdetails anti-YTHDF2 Antikörper

Target: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YTHDF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QEVPLEKAKQ VLKIIASYKH TTSIFDDFSH YEKRQEEEES VKKERQGRGK

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against YTHDF2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human YTHDF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 579 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu YTHDF2

Target: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Andere Bezeichnung: YTHDF2 (YTHDF2 Produkte)

Synonyme: MGC82537 antikoerper, HGRG8 antikoerper, NY-REN-2 antikoerper, YTH N(6)-methyladenosine RNA binding protein 2 L homeolog antikoerper, YTH N6-methyladenosine RNA binding protein 2 antikoerper, ythdf2.L antikoerper, YTHDF2 antikoerper

Hintergrund: This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosme 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene.
Alias Symbols: HGRG8, NY-REN-2
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, RNF2, BMI1, EIF3H, EIF3A, FBXO6, TARDBP, HIPK4, VCAM1, FN1, EPAS1, ESR1, APP, SMAD3, CAND1, CUL3, ELAVL1, POT1, MEPCE, HNRNPH1, HNRNPA1,
Protein Size: 579

Molekulargewicht: 62 kDa

Gen-ID: 51441

NCBI Accession: NM_016258, NP_057342

UniProt: Q9Y5A9