YTHDF2 Antikörper (AA 201-500)

Produktnummer ABIN7175942

Produktdetails anti-YTHDF2 Antikörper

Target: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Bindungsspezifität: AA 201-500

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YTHDF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human YTH domain-containing family protein 2 protein (201-500AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu YTHDF2

Target: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Andere Bezeichnung: YTHDF2 (YTHDF2 Produkte)

Synonyme: MGC82537 antikoerper, HGRG8 antikoerper, NY-REN-2 antikoerper, YTH N(6)-methyladenosine RNA binding protein 2 L homeolog antikoerper, YTH N6-methyladenosine RNA binding protein 2 antikoerper, ythdf2.L antikoerper, YTHDF2 antikoerper

Hintergrund:

Background: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability (PubMed:24284625, PubMed:26046440). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:22575960, PubMed:24284625, PubMed:25412658, PubMed:25412661). Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation (PubMed:24284625, PubMed:26046440).

Aliases: 9430020E02Rik antibody, CAHL antibody, CLL associated antigen KW 14 antibody, CLL-associated antigen KW-14 antibody, HGRG8 antibody, High glucose regulated protein 8 antibody, High-glucose-regulated protein 8 antibody, NY REN 2 antibody, Renal carcinoma antigen NY REN 2 antibody, Renal carcinoma antigen NY-REN-2 antibody, YTH domain family 2 antibody, YTH domain family member 2 antibody, YTH domain family protein 2 antibody, YTH N6 methyladenosine RNA binding protein 2 antibody, YTHD2_HUMAN antibody, YTHDF 2 antibody, YTHDF2 antibody

UniProt: Q9Y5A9