POF1B Antikörper (N-Term)

Produktnummer ABIN2790494

Der Kaninchen Polyklonal anti-POF1B Antikörper wird verwendet zum Nachweis von POF1B in Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schwein und Hund. Er wurde validiert für WB.

Kurzübersicht für POF1B Antikörper (N-Term) (ABIN2790494)

Target: POF1B (Premature Ovarian Failure, 1B (POF1B))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schwein, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POF1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-POF1B Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: POF1B Antibody - N-terminal region

Sequenz: HYHCYHQSSQ AQQPPEKNVV YERVRTYSGP MNKVVQALDP FNSREVLSPL

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against POF1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human POF1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66639-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu POF1B

Target: POF1B (Premature Ovarian Failure, 1B (POF1B))

Andere Bezeichnung: POF1B

Hintergrund:

Background Information: Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined.

Alternative Symbols: POF, POF2B

Protein Name: Protein POF1B

Molekulargewicht: 65kDa

Gen-ID: 79983

NCBI Accession: NP_079197

UniProt: Q8WVV4