NKAP Antikörper (C-Term)

Produktnummer ABIN2790485

Der Kaninchen Polyklonal Anti-NKAP-Antikörper wurde für WB validiert. Er ist geeignet, NKAP in Proben von Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für NKAP Antikörper (C-Term) (ABIN2790485)

Target: NKAP (NFKB Activating Protein (NKAP))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NKAP Antikörper

Bindungsspezifität: C-Term

Sequenz: EAVRLRKENQ IYSADEKRAL ASFNQEERRK RENKILASFR EMVYRKTKGK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against NKAP. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NKAP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 415 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NKAP

Target: NKAP (NFKB Activating Protein (NKAP))

Andere Bezeichnung: NKAP

Hintergrund: This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
Alias Symbols: FLJ22626
Protein Interaction Partner: UBC, SRPK1, CSNK2A2, TTC14, FRA10AC1, NKAP, PRPF40A, RBMX2, DDX41, RBM39, PPIG, BUB3, PRPF3, U2AF1, PCBP2, DHX15, DHX8, CUL5, SUMO2, LUC7L2, CEP70, THAP1, FAM124A,
Protein Size: 415

Molekulargewicht: 46 kDa

Gen-ID: 79576

NCBI Accession: NM_024528, NP_078804

UniProt: Q8N5F7

Pathways: Stem Cell Maintenance, Phosphorylierungen bei SARS-CoV-2 Infektion