NKAP Antikörper (AA 10-90)

Produktnummer ABIN7230010

Der Kaninchen Polyklonal anti-NKAP Antikörper wird verwendet zum Nachweis von NKAP in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für NKAP Antikörper (AA 10-90) (ABIN7230010)

Target: NKAP (NFKB Activating Protein (NKAP))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NKAP Antikörper

Bindungsspezifität: AA 10-90

Verwendungszweck: Rabbit Anti-NKAP Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of NKAP protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NKAP protein at AA range: 10-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu NKAP

Target: NKAP (NFKB Activating Protein (NKAP))

Andere Bezeichnung: NKAP

Hintergrund: NF-kappa-B-activating proteinNKAP encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.

Molekulargewicht: 45kD

Gen-ID: 79576

UniProt: Q8N5F7

Pathways: Stem Cell Maintenance, Phosphorylierungen bei SARS-CoV-2 Infektion