D2HGDH Antikörper (N-Term)

Produktnummer ABIN2790470

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch D2HGDH in WB. Es zeigt Reaktivität gegenüber Proben von Human, Zebrafisch (Danio rerio), Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für D2HGDH Antikörper (N-Term) (ABIN2790470)

Target: D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

Reaktivität: Human, Zebrafisch (Danio rerio), Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser D2HGDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-D2HGDH Antikörper

Bindungsspezifität: N-Term

Sequenz: AFERIVPGGV VTDPEALQAP NVDWLRTLRG CSKVLLRPRT SEEVSHILRH

Homologie: Cow: 79%, Dog: 92%, Guinea Pig: 85%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 92%, Rat: 93%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against D2HGDH. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human D2HGDH

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu D2HGDH

Target: D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

Andere Bezeichnung: D2HGDH

Hintergrund: This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
Alias Symbols: D2HGD
Protein Size: 325

Molekulargewicht: 35 kDa

Gen-ID: 728294

NCBI Accession: NM_001287249, NP_001274178

UniProt: Q8N465