D2HGDH Antikörper (N-Term)

Produktnummer ABIN2790470

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch D2HGDH in WB. Er zeigt eine Reaktivität gegenüber Human, Zebrafisch (Danio rerio), Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für D2HGDH Antikörper (N-Term) (ABIN2790470)

Target: D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

Reaktivität: Human, Zebrafisch (Danio rerio), Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser D2HGDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-D2HGDH Antikörper

Bindungsspezifität: N-Term

Sequenz: AFERIVPGGV VTDPEALQAP NVDWLRTLRG CSKVLLRPRT SEEVSHILRH

Homologie: Cow: 79%, Dog: 92%, Guinea Pig: 85%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 92%, Rat: 93%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against D2HGDH. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human D2HGDH

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu D2HGDH

Target: D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

Andere Bezeichnung: D2HGDH

Hintergrund: This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
Alias Symbols: D2HGD
Protein Size: 325

Molekulargewicht: 35 kDa

Gen-ID: 728294

NCBI Accession: NM_001287249, NP_001274178

UniProt: Q8N465