D2HGDH Antikörper (C-Term)
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- Target Alle D2HGDH Antikörper anzeigen
- D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Hund, Pferd, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser D2HGDH Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- QESPFYVLIE TSGSNAGHDA EKLGHFLEHA LGSGLVTDGT MATDQRKVKM
- Homologie
- Dog: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 77%, Rabbit: 100%, Rat: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against D2HGDH. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human D2HGDH
- Top Product
- Discover our top product D2HGDH Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 521 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))
- Andere Bezeichnung
- D2HGDH (D2HGDH Produkte)
- Synonyme
- AA408776 antikoerper, AA408778 antikoerper, AI325464 antikoerper, RGD1307976 antikoerper, D2HGD antikoerper, zgc:158661 antikoerper, D-2-hydroxyglutarate dehydrogenase antikoerper, D2hgdh antikoerper, D2HGDH antikoerper, d2hgdh antikoerper
- Hintergrund
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This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
Alias Symbols: D2HGD, FLJ42195, MGC25181
Protein Interaction Partner: SUMO1, UBC,
Protein Size: 521 - Molekulargewicht
- 55 kDa
- Gen-ID
- 728294
- NCBI Accession
- NM_152783, NP_689996
- UniProt
- Q8N465
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