CHRDL2 Antikörper (N-Term)
Kurzübersicht für CHRDL2 Antikörper (N-Term) (ABIN2790324)
Target
Alle CHRDL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- CTEGQIYCGL TTCPEPGCPA PLPLPDSCCQ ACKDEASEQS DEEDSVQSLH
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Homologie
- Human: 100%, Mouse: 83%, Rat: 75%, Yeast: 90%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CHRDL2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CHRDL2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 451 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CHRDL2 (Chordin-Like 2 (CHRDL2))
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Andere Bezeichnung
- CHRDL2
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Hintergrund
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CHRDL2 is implicated in tumor angiogenesis. CHRDL2 may inhibits BMPs activity by blocking their interaction with their receptors. CHRDL2 has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. CHRDL2 may play a role during myoblast and osteoblast differentiation, and maturation.
Alias Symbols: BNF1, CHL2, DKFZp586N2124, FKSG37
Protein Interaction Partner: GDF5, INHBA, BMP7, BMP6, BMP5, BMP4, BMP2,
Protein Size: 451 -
Molekulargewicht
- 3 kDa
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Gen-ID
- 25884
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NCBI Accession
- NM_015424, NP_056239
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UniProt
- Q6WN34
Target
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