CHRDL2 Antikörper (N-Term)

Produktnummer ABIN2790324

Produktdetails anti-CHRDL2 Antikörper

Target: CHRDL2 (Chordin-Like 2 (CHRDL2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRDL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CTEGQIYCGL TTCPEPGCPA PLPLPDSCCQ ACKDEASEQS DEEDSVQSLH

Homologie: Human: 100%, Mouse: 83%, Rat: 75%, Yeast: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against CHRDL2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CHRDL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 451 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CHRDL2

Target: CHRDL2 (Chordin-Like 2 (CHRDL2))

Andere Bezeichnung: CHRDL2 (CHRDL2 Produkte)

Hintergrund: CHRDL2 is implicated in tumor angiogenesis. CHRDL2 may inhibits BMPs activity by blocking their interaction with their receptors. CHRDL2 has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. CHRDL2 may play a role during myoblast and osteoblast differentiation, and maturation.
Alias Symbols: BNF1, CHL2, DKFZp586N2124, FKSG37
Protein Interaction Partner: GDF5, INHBA, BMP7, BMP6, BMP5, BMP4, BMP2,
Protein Size: 451

Molekulargewicht: 3 kDa

Gen-ID: 25884

NCBI Accession: NM_015424, NP_056239

UniProt: Q6WN34