EIF3I Antikörper (C-Term)

Produktnummer ABIN2789974

Produktdetails anti-EIF3I Antikörper

Target: EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF3I Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequenz: NVKEHSRQIN DIQLSRDMTM FVTASKDNTA KLFDSTTLEH QKTFRTERPV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF3I. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 325 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF3I

Target: EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))

Andere Bezeichnung: EIF3I (EIF3I Produkte)

Synonyme: EIF3S2 antikoerper, PRO2242 antikoerper, TRIP-1 antikoerper, TRIP1 antikoerper, eIF3-beta antikoerper, eIF3-p36 antikoerper, 36kDa antikoerper, D4Ertd632e antikoerper, Eif3s2 antikoerper, Trip1 antikoerper, eIF-3-beta antikoerper, eIF3 p36 antikoerper, eif3s2 antikoerper, hm:zehn0464 antikoerper, wu:fb62b08 antikoerper, zgc:56211 antikoerper, zgc:77823 antikoerper, CaO19.2967 antikoerper, eIF-3 39 kDa subunit homolog antikoerper, eIF3i antikoerper, eif3-beta antikoerper, eif3-p36 antikoerper, eif3i antikoerper, pro2242 antikoerper, trip-1 antikoerper, trip1 antikoerper, eukaryotic translation initiation factor 3 subunit I antikoerper, eukaryotic translation initiation factor 3, subunit I antikoerper, Eukaryotic Initiation Factor antikoerper, Eukaryotic translation initiation factor 3 subunit I antikoerper, translation initiation factor eIF3 subunit i antikoerper, eukaryotic translation initiation factor 3 subunit I L homeolog antikoerper, EIF3I antikoerper, Eif3i antikoerper, eif-3.I antikoerper, eIF3i antikoerper, eif3i antikoerper, TIF34 antikoerper, eif3i.L antikoerper

Hintergrund: EIF3I is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Alias Symbols: EIF3S2, PRO2242, TRIP-1, TRIP1, eIF3-beta, eIF3-p36
Protein Interaction Partner: HUWE1, UBC, SUMO2, SUMO3, RNF2, rev, EIF3G, HECW2, EIF3B, CDK18, TARDBP, NPM1, ICAM1, CD81, IGSF8, PAN2, EIF3D, VCAM1, ITGA4, METTL18, gag-pol, DDX3X, PAXIP1, LIG4, EIF3L, EIF3K, EIF3M, EIF3H, EIF3F, EIF3C, EIF3A, EIF3E, CUL3, CDK2, YWHAZ, SIRT7, ARRB1, R
Protein Size: 325

Molekulargewicht: 36 kDa

Gen-ID: 8668

NCBI Accession: NM_003757, NP_003748

UniProt: Q13347

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA