IDO1 Antikörper (C-Term)

Produktnummer ABIN2789915

Dieses Anti-IDO1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IDO1 in WB. Geeignet für Human, Schwein und Kaninchen.

Kurzübersicht für IDO1 Antikörper (C-Term) (ABIN2789915)

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reaktivität: Human, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IDO1 Antikörper

Bindungsspezifität: C-Term

Sequenz: ILIPASQQPK ENKTSEDPSK LEAKGTGGTD LMNFLKTVRS TTEKSLLKEG

Homologie: Human: 100%, Pig: 79%, Rabbit: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against IDO1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 403 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IDO1

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Andere Bezeichnung: IDO1

Hintergrund: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
Alias Symbols: IDO, INDO, IDO-1
Protein Interaction Partner: UBC, APP, TERF2IP, PPP1R16A, DDX24,
Protein Size: 403

Molekulargewicht: 45 kDa

Gen-ID: 3620

NCBI Accession: NM_002164, NP_002155

UniProt: P14902

Pathways: Activated T Cell Proliferation