IDO1 Antikörper (AA 204-403)

Produktnummer ABIN1513093

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IDO1 in WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IDO1 Antikörper (AA 204-403) (ABIN1513093)

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-IDO1 Antikörper

Bindungsspezifität: AA 204-403

Sequenz: ASCLEKALQV FHQIHDHVNP KAFFSVLRIY LSGWKGNPQL SDGLVYEGFW EDPKEFAGGS AGQSSVFQCF DVLLGIQQTA GGGHAAQFLQ DMRRYMPPAH RNFLCSLESN PSVREFVLSK GDAGLREAYD ACVKALVSLR SYHLQIVTKY ILIPASQQPK ENKTSEDPSK LEAKGTGGTD LMNFLKTVRS TTEKSLLKEG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 204-403 of human IDO1 (NP_002155.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IDO1

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Andere Bezeichnung: IDO1

Hintergrund: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.,IDO1,IDO,IDO-1,INDO,indoleamine 2,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Immunology & Inflammation,Cardiovascular,IDO1

Molekulargewicht: 45 kDa

Gen-ID: 3620

UniProt: P14902

Pathways: Activated T Cell Proliferation