PDE8B Antikörper (Middle Region)

Produktnummer ABIN2789902

Produktdetails anti-PDE8B Antikörper

Target: PDE8B (phosphodiesterase 8B (PDE8B))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Pferd, Rind (Kuh), Hund, Schwein, Meerschweinchen, Ratte, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE8B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TELYSPQLGT KDEDPHTSDL VGGLMTDGLR RLSGNEYVFT KNVHQSHSHL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PDE8B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 788 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDE8B

Target: PDE8B (phosphodiesterase 8B (PDE8B))

Andere Bezeichnung: PDE8B (PDE8B Produkte)

Synonyme: PDE8B antikoerper, ADSD antikoerper, PPNAD3 antikoerper, B230331L10Rik antikoerper, C030047E14Rik antikoerper, RNPDE8B antikoerper, phosphodiesterase 8B antikoerper, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B antikoerper, PDE8B antikoerper, LOC100468338 antikoerper, pde8b antikoerper, Pde8b antikoerper

Hintergrund: The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADSD, FLJ11212, PPNAD3
Protein Interaction Partner: UBC,
Protein Size: 788

Molekulargewicht: 87 kDa

Gen-ID: 8622

NCBI Accession: NM_001029851, NP_001025022

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process