MMP17 Antikörper (C-Term)

Produktnummer ABIN2789884

Dieses Anti-MMP17-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MMP17 in WB. Geeignet für Human, Rind (Kuh) und Pferd.

Kurzübersicht für MMP17 Antikörper (C-Term) (ABIN2789884)

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Reaktivität: Human, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MMP17 Antikörper

Bindungsspezifität: C-Term

Sequenz: YPQSTARDWL VCGDSQADGS VAAGVDAAEG PRAPPGQHDQ SRSEDGYEVC

Homologie: Cow: 79%, Horse: 93%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MMP17. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 603 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MMP17

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Andere Bezeichnung: MMP17

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
Alias Symbols: MT4-MMP
Protein Interaction Partner: TNF, MMP2, LRP1,
Protein Size: 603

Molekulargewicht: 66 kDa

Gen-ID: 4326

NCBI Accession: NM_016155, NP_057239

UniProt: Q9ULZ9