CD51 Antikörper (C-Term)

Produktnummer ABIN2789883

Der Kaninchen Polyklonal anti-CD51 Antikörper (ABIN2789883) detektiert spezifisch CD51 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Ziege, Meerschweinchen, Pferd und Schaf.

Kurzübersicht für CD51 Antikörper (C-Term) (ABIN2789883)

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Ziege, Meerschweinchen, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD51 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD51 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ITGAV Antibody - C-terminal region

Sequenz: PVWVIILAVL AGLLLLAVLV FVMYRMGFFK RVRPPQEEQE REQLQPHENG

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ITGAV. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ITGAV

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64575-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Andere Bezeichnung: ITGAV

Hintergrund:

Background Information: ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.

Alternative Symbols: CD51, MSK8, VNRA, VTNR

Protein Name: Integrin alpha-V light chain Ensembl ENSP00000404291

Molekulargewicht: 100kDa

Gen-ID: 3685

NCBI Accession: NP_001138471

UniProt: E7EWZ6

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex