CD51 Antikörper (C-Term)

Produktnummer ABIN2789883

Produktdetails anti-CD51 Antikörper

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Ziege, Meerschweinchen, Pferd, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD51 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PVWVIILAVL AGLLLLAVLV FVMYRMGFFK RVRPPQEEQE REQLQPHENG

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ITGAV. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ITGAV

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1002 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Andere Bezeichnung: ITGAV (ITGAV Produkte)

Hintergrund: ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.
Alias Symbols: CD51, DKFZp686A08142, MSK8, VNRA
Protein Interaction Partner: UBC, EPHA2, THBS1, FN1, KRT3, MCAT, FBXO6, BCAR1, PXN, PHKA2, CSF1R, CBL, MMP2, ILK, PLP1, CALR, ANGPTL3, EDIL3, CYR61, PAK4, ITGB8, ADAM9, AUP1, CD47, PTK2, MMP14, P2RY2, L1CAM, AZGP1, TGFB1, THY1, F2R, PDGFRA, ITGB3, SPP1, ITGB5, ITGB6, ITGB1, NID1, ICA
Protein Size: 1002

Molekulargewicht: 100 kDa

Gen-ID: 3685

NCBI Accession: NM_001144999, NP_001138471

UniProt: E7EWZ6

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex