JAM2 Antikörper (Middle Region)
Kurzübersicht für JAM2 Antikörper (Middle Region) (ABIN2789839)
Target
Alle JAM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- LVAPAVPSCE VPSSALSGTV VELRCQDKEG NPAPEYTWFK DGIRLLENPR
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against JAM2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human JAM2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 298 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- JAM2 (Junctional Adhesion Molecule 2 (JAM2))
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Andere Bezeichnung
- JAM2
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Hintergrund
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Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
Alias Symbols: C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM
Protein Interaction Partner: JAM3, JAM2, CSNK1A1L, TDP2, SOX8, YBX1, NME3, GPR20, F2RL2, TJP1, PARD3,
Protein Size: 298 -
Molekulargewicht
- 31 kDa
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Gen-ID
- 58494
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NCBI Accession
- NM_021219, NP_067042
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UniProt
- P57087
Target
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