SYNGAP1 Antikörper (C-Term)

Produktnummer ABIN2789829

Der Kaninchen Polyklonal anti-SYNGAP1 Antikörper wird verwendet zum Nachweis von SYNGAP1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Pferd, Kaninchen und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für SYNGAP1 Antikörper (C-Term) (ABIN2789829)

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYNGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SYNGAP1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SYNGAP1 Antibody - C-terminal region

Sequenz: EYKLKEYSKS MDESRLDRVK EYEEEIHSLK ERLHMSNRKL EEYERRLLSQ

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SYNGAP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64403-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SYNGAP1

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Andere Bezeichnung: SYNGAP1

Hintergrund:

Background Information: The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).

Gene Name: Synaptic Ras GTPase activating protein 1

Alternative Symbols: MRD5, RASA1, RASA5, SYNGAP

Protein Name: Ras GTPase-activating protein SynGAP

Molekulargewicht: 148kDa

Gen-ID: 8831

NCBI Accession: NP_006763

UniProt: Q96PV0

Pathways: Regulation of long-term Neuronal Synaptic Plasticity