SYNGAP1 Antikörper (C-Term)

Produktnummer ABIN2789829

Der Kaninchen Polyklonal Anti-SYNGAP1-Antikörper wurde für WB validiert. Er ist geeignet, SYNGAP1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Pferd, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für SYNGAP1 Antikörper (C-Term) (ABIN2789829)

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYNGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SYNGAP1 Antikörper

Bindungsspezifität: C-Term

Sequenz: EYKLKEYSKS MDESRLDRVK EYEEEIHSLK ERLHMSNRKL EEYERRLLSQ

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SYNGAP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1343 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SYNGAP1

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Andere Bezeichnung: SYNGAP1

Hintergrund: The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
Alias Symbols: DKFZp761G1421, KIAA1938, MRD5, RASA1, RASA5, SYNGAP
Protein Interaction Partner: SAAL1, DLGAP4, GRIN1, ULK1, ULK2, MPDZ, CAMK2A, TRIP6, DLG4, GRIN2D, DLG3, KDR, PDGFRB, GRIN2B,
Protein Size: 1343

Molekulargewicht: 148 kDa

Gen-ID: 8831

NCBI Accession: NM_006772, NP_006763

UniProt: Q96PV0

Pathways: Regulation of long-term Neuronal Synaptic Plasticity