PDE4C Antikörper (C-Term)

Produktnummer ABIN2789817

Der Kaninchen Polyklonal anti-PDE4C Antikörper wird verwendet zum Nachweis von PDE4C in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für PDE4C Antikörper (C-Term) (ABIN2789817)

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE4C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDE4C Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PDE4C Antibody - C-terminal region

Sequenz: RIMAEFFQQG DRERESGLDI SPMCDKHTAS VEKSQVGFID YIAHPLWETW

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 79%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PDE4C. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64361-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PDE4C

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Andere Bezeichnung: PDE4C

Hintergrund:

Background Information: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: Phosphodiesterase 4C, cAMP-specific

Alternative Symbols: DPDE1, PDE21

Protein Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4C

Molekulargewicht: 68kDa

Gen-ID: 5143

NCBI Accession: NP_001092289

UniProt: Q08493

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process