PDE4C Antikörper (AA 260-340)

Produktnummer ABIN7216476

Der Kaninchen Polyklonal anti-PDE4C Antikörper (ABIN7216476) detektiert spezifisch PDE4C in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PDE4C Antikörper (AA 260-340) (ABIN7216476)

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE4C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PDE4C Antikörper

Bindungsspezifität: AA 260-340

Verwendungszweck: Rabbit Anti-PDE4C Polyclonal Antibody

Spezifität: PDE4C Polyclonal Antibody detects endogenous levels of PDE4C protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PDE4C at AA range: 260-340

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PDE4C

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Andere Bezeichnung: PDE4C

Hintergrund: PDE4C, DPDE1, cAMP-specific 3', 5'-cyclic phosphodiesterase 4C, DPDE1, PDE21Phosphodiesterase 4C encoded by PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, phosphodiesterase 4C plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE4C.

Molekulargewicht: 80kD

Gen-ID: 5143

UniProt: Q08493

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process