S1PR1 Antikörper (C-Term)

Produktnummer ABIN2789809

Dieses Anti-S1PR1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von S1PR1 in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Kaninchen, Pferd und Meerschweinchen.

Kurzübersicht für S1PR1 Antikörper (C-Term) (ABIN2789809)

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S1PR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-S1PR1 Antikörper

Bindungsspezifität: C-Term

Sequenz: SLVRTRSRRL TFRKNISKAS RSSEKSLALL KTVIIVLSVF IACWAPLFIL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against S1PR1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 382 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Andere Bezeichnung: S1PR1

Hintergrund: The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.
Alias Symbols: CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, FLJ58121, S1P1
Protein Interaction Partner: UBC, CMSS1, WWP2, TRIP6, CAV1, HTR1D, PDGFRB, AKT1, GNAI3, GNAI1, HTR1A,
Protein Size: 382

Molekulargewicht: 43 kDa

Gen-ID: 1901

NCBI Accession: NM_001400, NP_001391

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2