S1PR1 Antikörper (C-Term)

Produktnummer ABIN2789809

Dieser Anti-S1PR1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von S1PR1 in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Kaninchen, Pferd und Meerschweinchen.

Kurzübersicht für S1PR1 Antikörper (C-Term) (ABIN2789809)

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S1PR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-S1PR1 Antikörper

Bindungsspezifität: C-Term

Sequenz: SLVRTRSRRL TFRKNISKAS RSSEKSLALL KTVIIVLSVF IACWAPLFIL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against S1PR1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 382 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Andere Bezeichnung: S1PR1

Hintergrund: The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.
Alias Symbols: CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, FLJ58121, S1P1
Protein Interaction Partner: UBC, CMSS1, WWP2, TRIP6, CAV1, HTR1D, PDGFRB, AKT1, GNAI3, GNAI1, HTR1A,
Protein Size: 382

Molekulargewicht: 43 kDa

Gen-ID: 1901

NCBI Accession: NM_001400, NP_001391

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2