JIP3 Antikörper (N-Term)

Produktnummer ABIN2789770

Dieses Anti-JIP3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von JIP3 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio).

Kurzübersicht für JIP3 Antikörper (N-Term) (ABIN2789770)

Target: JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JIP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-JIP3 Antikörper

Bindungsspezifität: N-Term

Sequenz: QYEREKALRR QAEEKFIEFE DALEQEKKEL QIQVEHYEFQ TRQLELKAKN

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Yeast: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MAPK8IP3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1330 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu JIP3

Target: JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))

Andere Bezeichnung: MAPK8IP3

Hintergrund: The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport.
Alias Symbols: DKFZp762N1113, FLJ00027, JIP3, JSAP1, KIAA1066, SYD2, syd
Protein Interaction Partner: MAP2K3, MAP3K5, BCL6, KAT2A, ALK, KLC2, RIC8A, MAPK8IP3, MAPK8IP2, TLR9, MAPK8IP1, TLR4, TLR2, MAP2K7, MAPK10, MAPK9, MAP2K4, MAPK8, PTK2, ARL4D, CASP3, MAP3K11, KLC1, MAP2K1, RAF1, MAP3K1, SRC,
Protein Size: 1330

Molekulargewicht: 147 kDa

Gen-ID: 23162

NCBI Accession: NM_001040439, NP_001035529

UniProt: E9PFH7