UNC13D Antikörper (C-Term)
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- Target Alle UNC13D Antikörper anzeigen
- UNC13D (Unc-13 Homolog D (UNC13D))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UNC13D Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SGSEEPGEVP QTRLPLTYPA PNGDPILQLL EGRKGDREAQ VFVRLRRHRA
- Homologie
- Cow: 92%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against UNC13D. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human UNC13D
- Top Product
- Discover our top product UNC13D Primärantikörper
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anti-Unc-13 Homolog D (UNC13D) (AA 2-100) antibody
UNC13D Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2C7 unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyUNC13D Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (Internal Region) antibodyVerified UNC13D Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 7-172) antibodyUNC13D Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 1-1090) antibodyUNC13D Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) antibodyUNC13D Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 1-1090) antibodyUNC13D Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyUNC13D Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 891-1090) antibodyUNC13D Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyVerified UNC13D Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeat freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- UNC13D (Unc-13 Homolog D (UNC13D))
- Andere Bezeichnung
- UNC13D (UNC13D Produkte)
- Hintergrund
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This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Alias Symbols: FHL3, HLH3, HPLH3, Munc13-4
Protein Interaction Partner: UBC, CUL5, VPS37B, XRN2, LMNA, RAB27B, RAB27A,
Protein Size: 1090 - Molekulargewicht
- 119 kDa
- Gen-ID
- 201294
- NCBI Accession
- NM_199242, NP_954712
- UniProt
- Q70J99
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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