GPBAR1 Antikörper (C-Term)

Produktnummer ABIN2789752

Der Kaninchen Polyklonal anti-GPBAR1 Antikörper wird verwendet zum Nachweis von GPBAR1 in Proben von Human und Ratte. Er wurde validiert für WB.

Kurzübersicht für GPBAR1 Antikörper (C-Term) (ABIN2789752)

Target: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPBAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GPBAR1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: GPBAR1 Antibody - C-terminal region

Sequenz: AAAVPVAMGL GDQRYTAPWR AAAQRCLQGL WGRASRDSPG PSIAYHPSSQ

Homologie: Human: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GPBAR1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64154-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GPBAR1

Target: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Andere Bezeichnung: GPBAR1

Hintergrund:

Background Information: This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.

Gene Name: G protein-coupled bile acid receptor 1

Alternative Symbols: BG37, TGR5, M-BAR, GPCR19, GPR131

Protein Name: G-protein coupled bile acid receptor 1

Molekulargewicht: 35kDa

Gen-ID: 151306

NCBI Accession: NP_733800

UniProt: Q8TDU6

Pathways: WNT Signalweg, Hormone Transport, Sensory Perception of Sound